LeishNatDrug

1. De Doncker,S., Hutse,V., Abdellati,S., Rijal,S., Singh Karki,B.M., Decuypere,S., Jacquet,D., Le Ray,D., Boelaert,M., Koirala,S. et al. (2005) A new PCR-ELISA for diagnosis of visceral leishmaniasis in blood of HIV-negative subjects. Trans.R.Soc.Trop Med Hyg, 99, 25-31. (Abstract)
2. Decuypere,S., Vandesompele,J., Yardley,V., De Doncker,S., Laurent,T., Rijal,S., Llanos-Cuentas,A., Chappuis,F., Arevalo,J. and Dujardin,J.C. (2005) Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, 131, 321-9 (Full Text).
3. Sangster,N.C., Upcroft,P., Upcroft,J.A., Geerts,S., Duraisingh,M., Decuypere,S. and Dujardin,J.C. (2005) Drug resistance assays for parasites. Antimicrobial drug resistance: principles and practice for the clinic and the bench. in press.
4. Tintaya,K.W., Ying,X., Dedet,J.P., Rijal,S., De,B., X and Dujardin,J.C. (2004) Antigen genes for molecular epidemiology of leishmaniasis: polymorphism of cysteine proteinase B and surface metalloprotease glycoprotein 63 in the Leishmania donovani complex. J Infect.Dis., 189, 1035-1043. (Abstract)
5. Yardley,V., Croft,S.L., De Doncker,S., Dujardin,J.C., Koirala,S., Rijal,S., Miranda,C. and Llanos-Cuentas,A. (2005) The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. Am J Trop Med Hyg, in press.

ITMA

1. Dujardin,J.C., Gajendran,N., Hamers,R., Mathijsen,G., Urjel,R., Recacoechea,M., Villaroel,G., Bermudez,H., Desjeux,P., De Doncker,S. et al. (1987) Leishmaniasis in the lowlands of Bolivia. VII Characterization and identification of Bolivian isolates by PFG karyotyping. In Hart,D. (ed.), Leishmaniasis: the first centenary (1885-1985). New strategies for control. Plenum Press, New York, Vol. 163, pp. 137-148.
2. Urjel,R., Recacoechea,M., Desjeux,P., Bermudez,H., Villaroel,G., Balderrama,S., Carrasco,J., Aguilar,O., Dujardin,J.C. and Le Ray,D. (1987) Leishmaniasis in the Lowlands of Bolivia. VI. Preliminary characterization of 11 Leishmania isolates. In Hart,D. (ed.), Leishmaniasis: the first centenary (1885-1985). New strategies for control. Plenum Press, New York, Vol. 163, pp. 131-136.
3. Recacoechea,M., Villaroel,G., Bermudez,H., Urjel,R., Dujardin,J.C. and Le Ray,D. (1987) Leishmaniasis in the Lowlands of Bolivia (LEISHBOL): I. An overview of the integrated project for the characterization, vigilance and control of leishmaniasis. In Hart,D. (ed.), Leishmaniasis: the first centenary (1885-1985). New strategies for control. Plenum Press, New York, Vol. 163, pp. 95-103.
4. Gajendran,N., Dujardin,J.C., Le Ray,D., Mathijsen,G., Muyldermans,S. and Hamers,R. (1987) Abnormally migrating chromosomes identify Leishmania donovani strains. In Hart,D. (ed.), Leishmaniasis: the first centenary (1885-1985). New strategies for control. Plenum Press, New York, Vol. 163, pp. 539-547.
5. Hamers,R., Gajendran,N., Dujardin,J.C. and Stuart,K. (1987) Circular and linear forms of small nucleic acids in Leishmania. In Hart,D. (ed.), Leishmaniasis: the first centenary (1885-1985). New strategies for control. Plenum Press, New York, Vol. 163, pp. 985-988.
6. Bermudez,H., Recacoechea,M., Urjel,R., Villaroel,G., Dujardin,J.C. and Le Ray,D. (1987) Leishmaniasis in Bolivia: current situation. In Walton,B.C., Wijeyaratne,P.M. and Modabber,F. (eds.), Research on control strategies for the Leishmaniases. IDRC-MR, Vol. 184, pp. 78-90.
7. Liu,J.H., Gajendran,N., Muthui,D., Muyldermans,S., Dujardin,J.C., De Doncker,S., Jacquet,D., Le Ray,D., Mathieu-Daude,F. and Hamers,R. (1991) Chromosome rearrangement in Leishmania mexicana M379. Mol.Biochem.Parasitol, 46, 53-60. (Abstract)
8. Dujardin,J.C., Gajendran,N., Arevalo,J., Llanos-Cuentas,A., Guerra,H., Gomez,J., Arroyo,J., De Doncker,S., Jacquet,D., Hamers,R. et al. (1993) Karyotype polymorphism and conserved characters in the Leishmania (Viannia) braziliensis complex explored with chromosome-derived probes. Ann.Soc.Belg.Med Trop, 73, 101-118. (Abstract)
9. Dujardin,J.C., Arevalo,J., Llanos-Cuentas,A., Caceres,A. and Le Ray,D. (1993) From pulsed field to field: contribution of molecular karyotyping to epidemiological studies on New World leishmaniasis. Arch.Inst.Pasteur Tunis, 70, 505-515. (Abstract)
10. Dujardin,J.C., De Doncker,S., Victoir,K., Le Ray,D., Hamers,R. and Arevalo,J. (1994) Size polymorphism of chromosomes bearing gp63 genes in Leishmania of the braziliensis complex: indication of a rearrangement of the gp63 genes in L. braziliensis and L. peruviana. Ann.Trop Med Parasitol, 88, 445-448. (Abstract)
11. Dujardin,J.C., Dujardin,J.P., Tibayrenc,M., Timperman,G., De Doncker,S., Jacquet,D., Arevalo,J., Llanos-Cuentas,A., Guerra,H., Bermudez,H. et al. (1995) Karyotype plasticity in neotropical Leishmania: an index for measuring genomic distance among L. (V.) peruviana and L. (V.) braziliensis populations. Parasitology, 110 ( Pt 1), 21-30. (Abstract)
12. Dujardin,J.C., Banuls,A.L., Llanos-Cuentas,A., Alvarez,E., DeDoncker,S., Jacquet,D., Le Ray,D., Arevalo,J. and Tibayrenc,M. (1995) Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru. Acta Trop, 59, 293-307. (Abstract)
13. Victoir,K., Dujardin,J.C., De Doncker,S., Barker,D.C., Arevalo,J., Hamers,R. and Le Ray,D. (1995) Plasticity of gp63 gene organization in Leishmania (Viannia) braziliensis and Leishmania (Viannia) peruviana. Parasitology, 111 ( Pt 3), 265-273. (Abstract)
14. Dujardin,J.C., Banuls,A.L., Victoir,K., De Doncker,S., Arevalo,J., Llanos-Cuentas,A., Tibayrenc,M. and Le Ray,D. (1995) From population to genome: ecogenetics of Leishmania (Viannia) braziliensis and L. (V.) peruviana. Ann.Trop Med Parasitol, 89 Suppl 1, 45-53. (Abstract)
15. Dujardin, J. C. (1995) Significations de la variabilite caryotypique chez les populations naturelles de leishmanies Neotropicales. Doctoral Thesis, Vrije Universiteit Brussel.
16. Dujardin,J.C., Llanos-Cuentas,A., Caceres,A., Arana,M., Dujardin,J.P., Guerrini,F., Gomez,J., Arroyo,J., De Doncker,S., Jacquet,D. et al. (1993) Molecular karyotype variation in Leishmania (Viannia) peruviana: indication of geographical populations in Peru distributed along a north-south cline. Ann.Trop Med Parasitol, 87, 335-347. (Abstract)
17. Dujardin, J. C. (1997) Leishmanioses au Perou: signification eco-epidemiologique de la variablilite caryotypique. Memoires de l'Academie Royale des Sciences d'Outre-Mer.
18. Victoir,K., Banuls,A.L., Arevalo,J., Llanos-Cuentas,A., Hamers,R., Noel,S., De Doncker,S., Le Ray,D., Tibayrenc,M. and Dujardin,J.C. (1998) The gp63 gene locus, a target for genetic characterization of Leishmania belonging to subgenus Viannia. Parasitology, 117 ( Pt 1), 1-13. (Abstract)
19. Inga,R., De Doncker,S., Gomez,J., Lopez,M., Garcia,R., Le Ray,D., Arevalo,J. and Dujardin,J.C. (1998) Relation between variation in copy number of ribosomal RNA encoding genes and size of harbouring chromosomes in Leishmania of subgenus Viannia. Mol.Biochem.Parasitol, 92, 219-228. (Abstract)
20. Dujardin,J.C., Banuls,A.L., Dujardin,J.P., Arevalo,J., Tibayrenc,M. and Le Ray,D. (1998) Comparison of chromosome and isoenzyme polymorphism in geographical populations of Leishmania (Viannia) peruviana. Parasitology, 117 ( Pt 6), 547-554. (Abstract)
21. Martinez,E., Le Pont,F., Torrez,M., Telleria,J., Vargas,F., Munoz,M., De Doncker,S., Dujardin,J.C. and Dujardin,J.P. (1998) A new focus of cutaneous leishmaniasis due to Leishmania amazonensis in a Sub Andean region of Bolivia. Acta Trop, 71, 97-106. (Abstract)
22. Torrico,M.C., De Doncker,S., Arevalo,J., Le Ray,D. and Dujardin,J.C. (1999) In vitro promastigote fitness of putative Leishmania (Viannia) braziliensis/Leishmania (Viannia) peruviana hybrids. Acta Trop, 72, 99-110. (Abstract)
23. Kebede,A., De Doncker,S., Arevalo,J., Le Ray,D. and Dujardin,J.C. (1999) Size-polymorphism of mini-exon gene-bearing chromosomes among natural populations of Leishmania, subgenus Viannia. Int.J Parasitol, 29, 549-557. (Abstract)
24. Martinez,E., Le Pont,F., Torrez,M., Telleria,J., Vargas,F., Dujardin,J.C. and Dujardin,J.P. (1999) Lutzomyia nuneztovari anglesi (Le pont & Desjeux, 1984) as a vector of Leishmania amazonensis in a sub-Andean leishmaniasis focus of Bolivia. Am J Trop Med Hyg, 61, 846-849. (Abstract)
25. Colebunders,R., Depraetere,K., Verstraeten,T., Lambert,J., Hauben,E., Van Marck,E., Maurer,T., Banuls,A.L. and Dujardin,J.C. (1999) Unusual cutaneous lesions in two patients with visceral leishmaniasis and HIV infection. J Am Acad.Dermatol., 41, 847-850. (Abstract)
26. Boelaert,M. and Dujardin,J.C. (1999) Diagnostic PCR with Leishmania donovani specificity. Trop Med Int.Health, 4, 789. (Abstract)
27. Banuls,A.L., Dujardin,J.C., Guerrini,F., De Doncker,S., Jacquet,D., Arevalo,J., Noel,S., Le Ray,D. and Tibayrenc,M. (2000) Is Leishmania (Viannia) peruviana a distinct species? A MLEE/RAPD evolutionary genetics answer. J Eukaryot.Microbiol., 47, 197-207. (Abstract)
28. Guerbouj,S., Guizani,I., Victoir,K., Le Ray,D. and Dujardin,J.C. (2000) Parasite candidate vaccines: a warning from polymorphic Leishmania populations. Parasitol Today, 16, 265. (Abstract)
29. Brisse,S., Dujardin,J.C. and Tibayrenc,M. (2000) Identification of six Trypanosoma cruzi lineages by sequence-characterised amplified region markers. Mol.Biochem.Parasitol, 111, 95-105. (Abstract)
30. Dujardin,J.C., Henriksson,J., Victoir,K., Brisse,S., Gamboa,D., Arevalo,J. and Le Ray,D. (2000) Genomic rearrangements in trypanosomatids: an alternative to the “one gene” evolutionary hypotheses? Mem.Inst.Oswaldo Cruz, 95, 527-534. (Abstract)
31. Guerbouj,S., Victoir,K., Guizani,I., Seridi,N., Nuwayri-Salti,N., Belkaid,M., Ismail,R.B., Le Ray,D. and Dujardin,J.C. (2001) Gp63 gene polymorphism and population structure of Leishmania donovani complex: influence of the host selection pressure? Parasitology, 122 Pt 1, 25-35. (Abstract)
32. Couvreur,B., Bollen,A., Dujardin,J.C. and Le Ray,D. (2001) More panantigens in Leishmania. Trends Parasitol, 17, 63-64. (Abstract)
33. Guerbouj,S., Guizani,I., Speybroeck,N., Le Ray,D. and Dujardin,J.C. (2001) Genomic polymorphism of Leishmania infantum: a relationship with clinical pleomorphism? Infect.Genet.Evol., 1, 49-59. (Abstract)
34. Guerbouj,S., Guizani,I., De Doncker,S., Dujardin,J.C. and Nuwayri-Salti,N. (2001) Identification of Lebanese dermotropic putative Leishmania archibaldi isolates by gp63 PCR-RFLP. Trans.R.Soc.Trop Med Hyg, 95, 687-688. (Abstract)
35. Henriksson,J., Dujardin,J.C., Barnabe,C., Brisse,S., Timperman,G., Venegas,J., Pettersson,U., Tibayrenc,M. and Solari,A. (2002) Chromosomal size variation in Trypanosoma cruzi is mainly progressive and is evolutionarily informative. Parasitology, 124, 277-286. (Abstract)
36. Victoir,K. and Dujardin,J.C. (2002) How to succeed in parasitic life without sex? Asking Leishmania. Trends Parasitol, 18, 81-85. (Abstract)
37. Dujardin,J.C., Victoir,K., De Doncker,S., Guerbouj,S., Arevalo,J. and Le Ray,D. (2002) Molecular epidemiology and diagnosis of Leishmania: what have we learnt from genome structure, dynamics and function? Trans.R.Soc.Trop Med Hyg, 96 Suppl 1, S81-S86. (Abstract)
38. Couvreur,B., Wattiez,R., Bollen,A., Falmagne,P., Le Ray,D. and Dujardin,J.C. (2002) Eubacterial HslV and HslU subunits homologs in primordial eukaryotes. Mol.Biol.Evol., 19, 2110-2117. (Abstract)
39. Brisse,S., Henriksson,J., Barnabe,C., Douzery,E.J., Berkvens,D., Serrano,M., De Carvalho,M.R., Buck,G.A., Dujardin,J.C. and Tibayrenc,M. (2003) Evidence for genetic exchange and hybridization in Trypanosoma cruzi based on nucleotide sequences and molecular karyotype. Infect.Genet.Evol., 2, 173-183. (Abstract)
40. Victoir,K., De Doncker,S., Cabrera,L., Alvarez,E., Arevalo,J., Llanos-Cuentas,A., Le Ray,D. and Dujardin,J.C. (2003) Direct identification of Leishmania species in biopsies from patients with American tegumentary leishmaniasis. Trans.R.Soc.Trop Med Hyg, 97, 80-87. (Abstract)
41. Couvreur,B., Bollen,A., Le Ray,D. and Dujardin,J.C. (2003) Reverse transcription-polymerase chain reaction construction of plasmid-based, full-length cDNA libraries from Leishmania infantum for in vitro expression screening. Mem.Inst.Oswaldo Cruz, 98, 477-480. (Abstract)
42. Decuypere,S., Elinck,E., Van Overmeir,C., Talisuna,A.O., D'Alessandro,U. and Dujardin,J.C. (2003) Pathogen genotyping in polyclonal infections: application of a fluorogenic polymerase-chain-reaction assay in malaria. J Infect.Dis., 188, 1245-1249. (Abstract)
43. Tinto,H., Ouedraogo,J.B., Erhart,A., Van Overmeir,C., Dujardin,J.C., Van Marck,E., Guiguemde,T.R. and D'Alessandro,U. (2003) Relationship between the Pfcrt T76 and the Pfmdr-1 Y86 mutations in Plasmodium falciparum and in vitro/in vivo chloroquine resistance in Burkina Faso, West Africa. Infect.Genet.Evol., 3, 287-292. (Abstract)
44. Rwagacondo,C.E., Niyitegeka,F., Sarushi,J., Karema,C., Mugisha,V., Dujardin,J.C., Van Overmeir,C., van den,E.J. and D'Alessandro,U. (2003) Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate. Am J Trop Med Hyg, 68, 743-747. (Abstract)
45. Caceres,A.G., Villaseca,P., Dujardin,J.C., Banuls,A.L., Inga,R., Lopez,M., Arana,M., Le Ray,D. and Arevalo,J. (2004) Epidemiology of Andean cutaneous leishmaniasis: incrimination of Lutzomyia ayacuchensis (Diptera: psychodidae) as a vector of Leishmania in geographically isolated, upland valleys of Peru. Am J Trop Med Hyg, 70, 607-612. (Abstract)
46. Tintaya,K.W., Ying,X., Dedet,J.P., Rijal,S., De,B., X and Dujardin,J.C. (2004) Antigen genes for molecular epidemiology of leishmaniasis: polymorphism of cysteine proteinase B and surface metalloprotease glycoprotein 63 in the Leishmania donovani complex. J Infect.Dis., 189, 1035-1043. (Abstract)
47. Marlet,M.V., Wuillaume,F., Jacquet,D., Tintaya,K.W., Dujardin,J.C. and Boelaert,M. (2004) A neglected disease of people forgotten: a new focus of visceral leishmaniasis in Bakool, Somalia. Trans.R.Soc.Trop Med Hyg, in press.
48. Garcia,L., Kindt,A., Bermudez,H., Llanos-Cuentas,A., De Doncker,S., Arevalo,J., Wilber Quispe,T.K. and Dujardin,J.C. (2004) Culture-independent species typing of neotropical Leishmania for clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J Clin.Microbiol., 42, 2294-2297. (Abstract)
49. Rwagacondo,C.E., Karema,C., Mugisha,V., Erhart,A., Dujardin,J.C., Van Overmeir,C., Ringwald,P. and D'Alessandro,U. (2004) Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria. Trop Med Int.Health, 9, 1091-1098. (Abstract)
50. De Doncker,S., Hutse,V., Abdellati,S., Rijal,S., Singh Karki,B.M., Decuypere,S., Jacquet,D., Le Ray,D., Boelaert,M., Koirala,S. et al. (2005) A new PCR-ELISA for diagnosis of visceral leishmaniasis in blood of HIV-negative subjects. Trans.R.Soc.Trop Med Hyg, 99, 25-31. (Abstract)
51. Garcia,A.L., Kindt,A., Quispe-Tintaya,K.W., Bermudez,H., Llanos,A., Arevalo,J., Banuls,A.L., De Doncker,S., Le Ray,D. and Dujardin,J.C. (2005) American tegumentary leishmaniasis: antigen-gene polymorphism, taxonomy and clinical pleomorphism. Infect.Genet.Evol., 5, 109-116. (Abstract)
52. Yardley,V., Croft,S.L., De Doncker,S., Dujardin,J.C., Koirala,S., Rijal,S., Miranda,C. and Llanos-Cuentas,A. (2005) The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. Am J Trop Med Hyg, in press.
53. Tinto,H., Sanou,B., Dujardin,J.C., Ouedraogo,J.B., Van Overmeir,C., Erhart,A., Van Marck,E., Guiguemde,T.R. and D'Alessandro,U. (2005) Usefulness of the Pfcrt T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso. Am J Trop Med Hyg, in press.
54. Victoir,K., Arevalo,J., De Doncker,S., Barker,D.C., Laurent,T., Godfroid,E., Bollen,A., Le Ray,D. and Dujardin,J.C. (2005) Complexity of the major surface protease (msp) gene organisation in Leishmania (Viannia) braziliensis: evolutionary and functional implications. Parasitology, in press.
55. Decuypere,S., Vandesompele,J., Yardley,V., De Doncker,S., Laurent,T., Rijal,S., Llanos-Cuentas,A., Chappuis,F., Arevalo,J. and Dujardin,J.C. (2005) Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, in press.
56. Nyachieo,A., Van Overmeir,C., Laurent,T., Dujardin,J.C. and D'Alessandro,U. (2005) Plasmodium falciparum genotyping by microsatellites as a method to distinguish between recrudescent and new infections. Am J Trop Med Hyg, in press.
57. Sangster,N.C., Upcroft,P., Upcroft,J.A., Geerts,S., Duraisingh,M., Decuypere,S. and Dujardin,J.C. (2005) Drug resistance assays for parasites. Antimicrobial durg resistance: principles and practice for the clinic and the bench. in press.
58. Dujardin,J.C. (2005) Genomic rearrangements: a bubbling source of information for the molecular epidemiology of trypanosomatids. In Hide,G. (ed.), in press.

BPKIHS

1. Yardley,V., Croft,S.L., De Doncker,S., Dujardin,J.C., Koirala,S., Rijal,S., Miranda,C. and Llanos-Cuentas,A. (2005) The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. Am J Trop Med Hyg, in press.
2. Rijal,A., Agrawal,S., Agarwalla,A., Agrawal,A. and Rijal,S. (2005) Post-kala-azar dermal leishmaniasis with visceral leishmaniasis: a rare presentation. Int.J Dermatol., 44, 494-496. (Abstract)
3. De Doncker,S., Hutse,V., Abdellati,S., Rijal,S., Singh Karki,B.M., Decuypere,S., Jacquet,D., Le Ray,D., Boelaert,M., Koirala,S. et al. (2005) A new PCR-ELISA for diagnosis of visceral leishmaniasis in blood of HIV-negative subjects. Trans.R.Soc.Trop Med Hyg, 99, 25-31. (Abstract)
4. Rijal,S., Boelaert,M., Regmi,S., Karki,B.M., Jacquet,D., Singh,R., Chance,M.L., Chappuis,F., Hommel,M., Desjeux,P. et al. (2004) Evaluation of a urinary antigen-based latex agglutination test in the diagnosis of kala-azar in eastern Nepal. Trop Med Int.Health, 9, 724-729. (Abstract)
5. Boelaert,M., Rijal,S., Regmi,S., Singh,R., Karki,B., Jacquet,D., Chappuis,F., Campino,L., Desjeux,P., Le Ray,D. et al. (2004) A comparative study of the effectiveness of diagnostic tests for visceral leishmaniasis. Am J Trop Med Hyg, 70, 72-77. (Abstract)
6. Tintaya,K.W., Ying,X., Dedet,J.P., Rijal,S., De,B., X and Dujardin,J.C. (2004) Antigen genes for molecular epidemiology of leishmaniasis: polymorphism of cysteine proteinase B and surface metalloprotease glycoprotein 63 in the Leishmania donovani complex. J Infect.Dis., 189, 1035-1043. (Abstract)
7. Rijal,S., Chappuis,F., Singh,R., Bovier,P.A., Acharya,P., Karki,B.M., Das,M.L., Desjeux,P., Loutan,L. and Koirala,S. (2003) Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline. Trans.R.Soc.Trop Med Hyg, 97, 350-354. (Abstract)
8. Rijal,S., Chappuis,F., Singh,R., Boelaert,M., Loutan,L. and Koirala,S. (2003) Sodium stibogluconate cardiotoxicity and safety of generics. Trans.R.Soc.Trop Med Hyg, 97, 597-598. (Abstract)
9. Chappuis,F., Rijal,S., Singh,R., Acharya,P., Karki,B.M., Das,M.L., Bovier,P.A., Desjeux,P., Le Ray,D., Koirala,S. et al. (2003) Prospective evaluation and comparison of the direct agglutination test and an rK39-antigen-based dipstick test for the diagnosis of suspected kala-azar in Nepal. Trop Med Int.Health, 8, 277-285. (Abstract)
10. Sangraula,H., Sharma,K.K., Rijal,S., Dwivedi,S. and Koirala,S. (2003) Orally effective drugs for kala-azar (visceral leishmaniasis): focus on miltefosine and sitamaquine. J Assoc.Physicians India, 51, 686-690. (Abstract)
11. Sah,S.P., Rijal,S., Bhadani,P.P., Rani,S. and Koirala,S. (2002) Visceral leishmaniasis in two cases of leukemia. Southeast Asian J Trop Med Public Health, 33, 25-27. (Abstract)
12. Sharma,S.K., Das,M.L., Rijal,S., Sah,S.P. and Koirala,S. (2001) Lymphatic leishmaniasis--first case report from Nepal. Southeast Asian J Trop Med Public Health, 32, 749-750. (Abstract)

CUMETROP

1. Bermudez,H., Torrico,F., Rojas,E., Balderrama,F., Le Ray,D., Guerra,H. and Arevalo,J. (1993) Leishmaniasis in the lowlands of Bolivia, prevalence of the disease in two groups of localities with different settlement ages in Carrasco Tropical, Cochabamba. Arch.Inst.Pasteur Tunis, 70, 443-453. (Abstract)
2. Medrano-Mercado,N., Luz,M.R., Torrico,F., Tapia,G., Van Leuven,F. and Araujo-Jorge,T.C. (1996) Acute-phase proteins and serologic profiles of chagasic children from an endemic area in Bolivia. Am J Trop Med Hyg, 54, 154-161. (Abstract)
3. Torrico,M.C., De Doncker,S., Arevalo,J., Le Ray,D. and Dujardin,J.C. (1999) In vitro promastigote fitness of putative Leishmania (Viannia) braziliensis/Leishmania (Viannia) peruviana hybrids. Acta Trop, 72, 99-110. (Abstract)
4. Dujardin,J.C., Dujardin,J.P., Tibayrenc,M., Timperman,G., De Doncker,S., Jacquet,D., Arevalo,J., Llanos-Cuentas,A., Guerra,H., Bermudez,H. et al. (1995) Karyotype plasticity in neotropical Leishmania: an index for measuring genomic distance among L. (V.) peruviana and L. (V.) braziliensis populations. Parasitology, 110 ( Pt 1), 21-30. (Abstract)
5. Antas,P.R., Medrano-Mercado,N., Torrico,F., Ugarte-Fernandez,R., Gomez,F., Correa,O.R., Chaves,A.C., Romanha,A.J. and Araujo-Jorge,T.C. (1999) Early, intermediate, and late acute stages in Chagas' disease: a study combining anti-galactose IgG, specific serodiagnosis, and polymerase chain reaction analysis. Am J Trop Med Hyg, 61, 308-314. (Abstract)
6. Garcia,A.L., Kindt,A., Quispe-Tintaya,K.W., Bermudez,H., Llanos,A., Arevalo,J., Banuls,A.L., De Doncker,S., Le Ray,D. and Dujardin,J.C. (2005) American tegumentary leishmaniasis: antigen-gene polymorphism, taxonomy and clinical pleomorphism. Infect.Genet.Evol., 5, 109-116. (Abstract)
7. Garcia,L., Kindt,A., Bermudez,H., Llanos-Cuentas,A., De Doncker,S., Arevalo,J., Wilber Quispe,T.K. and Dujardin,J.C. (2004) Culture-independent species typing of neotropical Leishmania for clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J Clin.Microbiol., 42, 2294-2297. (Abstract)

LSHTM

1. Larabi,M., Yardley,V., Loiseau,P.M., Appel,M., Legrand,P., Gulik,A., Bories,C., Croft,S.L. and Barratt,G. (2003) Toxicity and antileishmanial activity of a new stable lipid suspension of amphotericin B. Antimicrob.Agents Chemother., 47, 3774-3779. (Abstract)
2. Yardley,V., Khan,A.A., Martin,M.B., Slifer,T.R., Araujo,F.G., Moreno,S.N., Docampo,R., Croft,S.L. and Oldfield,E. (2002) In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrob.Agents Chemother., 46, 929-931. (Abstract)
3. Croft,S.L. and Yardley,V. (2002) Chemotherapy of leishmaniasis. Curr.Pharm.Des, 8, 319-342. (Abstract)
4. Croft,S.L., Yardley,V. and Kendrick,H. (2002) Drug sensitivity of Leishmania species: some unresolved problems. Trans.R.Soc.Trop Med Hyg, 96 Suppl 1, S127-S129. (Abstract)
5. Martin,M.B., Grimley,J.S., Lewis,J.C., Heath,H.T., III, Bailey,B.N., Kendrick,H., Yardley,V., Caldera,A., Lira,R., Urbina,J.A. et al. (2001) Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. J Med Chem., 44, 909-916. (Abstract)
6. Escobar,P., Yardley,V. and Croft,S.L. (2001) Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. Antimicrob.Agents Chemother., 45, 1872-1875. (Abstract)
7. Yardley,V. and Croft,S.L. (2000) A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis. Int.J Antimicrob.Agents, 13, 243-248. (Abstract)
8. Smith,A.C., Yardley,V., Rhodes,J. and Croft,S.L. (2000) Activity of the novel immunomodulatory compound tucaresol against experimental visceral leishmaniasis. Antimicrob.Agents Chemother., 44, 1494-1498. (Abstract)
9. Davidson,R.N., Yardley,V., Croft,S.L., Konecny,P. and Benjamin,N. (2000) A topical nitric oxide-generating therapy for cutaneous leishmaniasis. Trans.R.Soc.Trop Med Hyg, 94, 319-322. (Abstract)
10. Yardley,V. and Croft,S.L. (2005) Animal models of cutaneous leishmaniasis. In Zak,O. (ed.), Handbook of Animal Models of Infection. Academic Press, New York, pp. 775-781.
11. Yardley,V. and Croft,S.L. (1999) In vitro and in vivo activity of amphotericin B-lipid formulations against experimental Trypanosoma cruzi infections. Am J Trop Med Hyg, 61, 193-197. (Abstract)
12. Petit,C., Yardley,V., Gaboriau,F., Bolard,J. and Croft,S.L. (1999) Activity of a heat-induced reformulation of amphotericin B deoxycholate (fungizone) against Leishmania donovani. Antimicrob.Agents Chemother., 43, 390-392. (Abstract)
13. Croft,S.L. and Yardley,V. (2005) Animal models of visceral leishmaniasis. In Zak,O. (ed.), Handbook of Animal Models of Infection. Academic Press, New York, pp. 783-787.
14. Yardley,V. and Croft,S.L. (1997) Activity of liposomal amphotericin B against experimental cutaneous leishmaniasis. Antimicrob.Agents Chemother., 41, 752-756. (Abstract)

IMTAvH

A. Unit of Cellular and Molecular Biology of Trypanosomatids

1. Decuypere,S., Vandesompele,J., Yardley,V., De Doncker,S., Laurent,T., Rijal,S., Llanos-Cuentas,A., Chappuis,F., Arevalo,J. and Dujardin,J.C. (2005) Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, in press.
2. Garcia,A.L., Kindt,A., Quispe-Tintaya,K.W., Bermudez,H., Llanos,A., Arevalo,J., Banuls,A.L., De Doncker,S., Le Ray,D. and Dujardin,J.C. (2005) American tegumentary leishmaniasis: antigen-gene polymorphism, taxonomy and clinical pleomorphism. Infect.Genet.Evol., 5, 109-116. (Abstract)
3. Caceres,A.G., Villaseca,P., Dujardin,J.C., Banuls,A.L., Inga,R., Lopez,M., Arana,M., Le Ray,D. and Arevalo,J. (2004) Epidemiology of Andean cutaneous leishmaniasis: incrimination of Lutzomyia ayacuchensis (Diptera: psychodidae) as a vector of Leishmania in geographically isolated, upland valleys of Peru. Am J Trop Med Hyg, 70, 607-612. (Abstract)
4. Garcia,L., Kindt,A., Bermudez,H., Llanos-Cuentas,A., De Doncker,S., Arevalo,J., Wilber Quispe,T.K. and Dujardin,J.C. (2004) Culture-independent species typing of neotropical Leishmania for clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J Clin.Microbiol., 42, 2294-2297. (Abstract)
5. Victoir,K., De Doncker,S., Cabrera,L., Alvarez,E., Arevalo,J., Llanos-Cuentas,A., Le Ray,D. and Dujardin,J.C. (2003) Direct identification of Leishmania species in biopsies from patients with American tegumentary leishmaniasis. Trans.R.Soc.Trop Med Hyg, 97, 80-87. (Abstract)
6. St Hilaire,P.M., Alves,L.C., Herrera,F., Renil,M., Sanderson,S.J., Mottram,J.C., Coombs,G.H., Juliano,M.A., Juliano,L., Arevalo,J. et al. (2002) Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana cysteine protease B. J Med Chem., 45, 1971-1982. (Abstract)
7. Dujardin,J.C., Victoir,K., De Doncker,S., Guerbouj,S., Arevalo,J. and Le Ray,D. (2002) Molecular epidemiology and diagnosis of Leishmania: what have we learnt from genome structure, dynamics and function? Trans.R.Soc.Trop Med Hyg, 96 Suppl 1, S81-S86. (Abstract)
8. Zimic,M.J., Guerra,D. and Arevalo,J. (2002) DNA thermodynamic pressure: a potential contributor to genome evolution. Trans.R.Soc.Trop Med Hyg, 96 Suppl 1, S15-S20. (Abstract)
9. Dujardin,J.C., Henriksson,J., Victoir,K., Brisse,S., Gamboa,D., Arevalo,J. and Le Ray,D. (2000) Genomic rearrangements in trypanosomatids: an alternative to the “one gene” evolutionary hypotheses? Mem.Inst.Oswaldo Cruz, 95, 527-534. (Abstract)
10. Banuls,A.L., Dujardin,J.C., Guerrini,F., De Doncker,S., Jacquet,D., Arevalo,J., Noel,S., Le Ray,D. and Tibayrenc,M. (2000) Is Leishmania (Viannia) peruviana a distinct species? A MLEE/RAPD evolutionary genetics answer. J Eukaryot.Microbiol., 47, 197-207. (Abstract)
11. Kebede,A., De Doncker,S., Arevalo,J., Le Ray,D. and Dujardin,J.C. (1999) Size-polymorphism of mini-exon gene-bearing chromosomes among natural populations of Leishmania, subgenus Viannia. Int.J Parasitol, 29, 549-557. (Abstract)
12. Dujardin,J.C., Banuls,A.L., Dujardin,J.P., Arevalo,J., Tibayrenc,M. and Le Ray,D. (1998) Comparison of chromosome and isoenzyme polymorphism in geographical populations of Leishmania (Viannia) peruviana. Parasitology, 117 ( Pt 6), 547-554. (Abstract)
13. Torrez,M., Lopez,M., Le Pont,F., Martinez,E., Munoz,M., Hervas,D., Yaksic,N., Arevalo,J., Sossa,D., Dedet,J.P. et al. (1998) Lutzomyia nuneztovari anglesi (Diptera: Psychodidae) as a probable vector of Leishmania braziliensis in the Yungas, Bolivia. Acta Trop, 71, 311-316. (Abstract)
14. Inga,R., De Doncker,S., Gomez,J., Lopez,M., Garcia,R., Le Ray,D., Arevalo,J. and Dujardin,J.C. (1998) Relation between variation in copy number of ribosomal RNA encoding genes and size of harbouring chromosomes in Leishmania of subgenus Viannia. Mol.Biochem.Parasitol, 92, 219-228. (Abstract)
15. Victoir,K., Banuls,A.L., Arevalo,J., Llanos-Cuentas,A., Hamers,R., Noel,S., De Doncker,S., Le Ray,D., Tibayrenc,M. and Dujardin,J.C. (1998) The gp63 gene locus, a target for genetic characterization of Leishmania belonging to subgenus Viannia. Parasitology, 117 ( Pt 1), 1-13. (Abstract)
16. Victoir,K., Dujardin,J.C., De Doncker,S., Barker,D.C., Arevalo,J., Hamers,R. and Le Ray,D. (1995) Plasticity of gp63 gene organization in Leishmania (Viannia) braziliensis and Leishmania (Viannia) peruviana. Parasitology, 111 ( Pt 3), 265-273. (Abstract)
17. Dujardin,J.C., Banuls,A.L., Victoir,K., De Doncker,S., Arevalo,J., Llanos-Cuentas,A., Tibayrenc,M. and Le Ray,D. (1995) From population to genome: ecogenetics of Leishmania (Viannia) braziliensis and L. (V.) peruviana. Ann.Trop Med Parasitol, 89 Suppl 1, 45-53. (Abstract)
18. Dujardin,J.C., Banuls,A.L., Llanos-Cuentas,A., Alvarez,E., DeDoncker,S., Jacquet,D., Le Ray,D., Arevalo,J. and Tibayrenc,M. (1995) Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru. Acta Trop, 59, 293-307. (Abstract)
19. Espinoza,J.R., Skinner,A.C., Davies,C.R., Llanos-Cuentas,A., Arevalo,J., Dye,C., McMaster,W.R., Ajioka,J.W. and Blackwell,J.M. (1995) Extensive polymorphism at the Gp63 locus in field isolates of Leishmania peruviana. Mol.Biochem.Parasitol, 72, 203-213. (Abstract)
20. Dujardin,J.C., Dujardin,J.P., Tibayrenc,M., Timperman,G., De Doncker,S., Jacquet,D., Arevalo,J., Llanos-Cuentas,A., Guerra,H., Bermudez,H. et al. (1995) Karyotype plasticity in neotropical Leishmania: an index for measuring genomic distance among L. (V.) peruviana and L. (V.) braziliensis populations. Parasitology, 110 ( Pt 1), 21-30. (Abstract)

B. Leishmania Working Group

1. Llanos-Cuentas,A., Echevarria,J., Cruz,M., La Rosa,A., Campos,P., Campos,M., Franke,E., Berman,J., Modabber,F. and Marr,J. (1997) Efficacy of sodium stibogluconate alone and in combination with allopurinol for treatment of mucocutaneous leishmaniasis. Clin.Infect.Dis., 25, 677-684. (Abstract)
2. Saiz,M., Llanos-Cuentas,A., Echevarria,J., Roncal,N., Cruz,M., Muniz,M.T., Lucas,C., Wirth,D.F., Scheffter,S., Magill,A.J. et al. (1998) Short report: detection of Leishmaniavirus in human biopsy samples of leishmaniasis from Peru. Am J Trop Med Hyg, 58, 192-194. (Abstract)
3. Llanos-Cuentas,E.A., Roncal,N., Villaseca,P., Paz,L., Ogusuku,E., Perez,J.E., Caceres,A. and Davies,C.R. (1999) Natural infections of Leishmania peruviana in animals in the Peruvian Andes. Trans.R.Soc.Trop Med Hyg, 93, 15-20. (Abstract)
4. Birtles,R.J., Canales,J., Ventosilla,P., Alvarez,E., Guerra,H., Llanos-Cuentas,A., Raoult,D., Doshi,N. and Harrison,T.G. (1999) Survey of Bartonella species infecting intradomicillary animals in the Huayllacallan Valley, Ancash, Peru, a region endemic for human bartonellosis. Am J Trop Med Hyg, 60, 799-805. (Abstract)
5. Echevarria,J. and Llanos-Cuentas,A. (1999) Infecciones tropicales en viajeros a Latinamerica. Parte I. Revista Chilena de Infectologia, 16, 321-27.
6. Davies,C.R., Llanos-Cuentas,E.A., Campos,P., Monge,J., Leon,E. and Canales,J. (2000) Spraying houses in the Peruvian Andes with lambda-cyhalothrin protects residents against cutaneous leishmaniasis. Trans.R.Soc.Trop Med Hyg, 94, 631-636. (Abstract)
7. Llanos-Cuentas,A., Campos,P., Clendenes,M., Canfield,C.J. and Hutchinson,D.B. (2001) Atovaquone and proguani hydrochloride compared with chloroquine or pyrimethamine/sulfodaxine for treatment of acute Plasmodium falciparum malaria in Peru. Braz.J Infect.Dis., 5, 67-72. (Abstract)
8. Arevalo,I., Ward,B., Miller,R., Meng,T.C., Najar,E., Alvarez,E., Matlashewski,G. and Llanos-Cuentas,A. (2001) Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator. Clin.Infect.Dis., 33, 1847-1851. (Abstract)
9. Guthmann,J.P., Hall,A.J., Jaffar,S., Palacios,A., Lines,J. and Llanos-Cuentas,A. (2001) Environmental risk factors for clinical malaria: a case-control study in the Grau region of Peru. Trans.R.Soc.Trop Med Hyg, 95, 577-583. (Abstract)
10. Guthmann,J.P., Llanos-Cuentas,A., Palacios,A. and Hall,A.J. (2002) Environmental factors as determinants of malaria risk. A descriptive study on the northern coast of Peru. Trop Med Int.Health, 7, 518-525. (Abstract)
11. Valdivia,R.M., Llanos-Cuentas,A., Zapata,S.C. and Munoz,O.N. (2002) La validez de la concentracio de proteinas en el liquido ascitico y suero para el diagnostico diferencial de la ascitis. Revista Gastroenterologica del Peru, 22, 279-286.
12. Solari-Soto,L., Soto-Tarazona,A., Mendoza-Requena,D. and Llanos-Cuentas,A. (2002) Ensayo clinico del tratamiento de la malaria vivax con esquiema acortado de primaquina comparado con el esquema tradicional. Revista de la Sociedad Peruana de Medicina Interna, 15, 196-99.
13. Victoir,K., De Doncker,S., Cabrera,L., Alvarez,E., Arevalo,J., Llanos-Cuentas,A., Le Ray,D. and Dujardin,J.C. (2003) Direct identification of Leishmania species in biopsies from patients with American tegumentary leishmaniasis. Trans.R.Soc.Trop Med Hyg, 97, 80-87. (Abstract)
14. Reithinger,R., Canales,E.J., Llanos-Cuentas,A. and Davies,C.R. (2003) Domestic dog ownership: a risk factor for human infection with Leishmania (Viannia) species. Trans.R.Soc.Trop Med Hyg, 97, 141-145. (Abstract)
15. Chinga-Alayo,E., Huarcaya,E., Nasarre,C., del Aguila,R. and Llanos-Cuentas,A. (2004) The influence of climate on the epidemiology of bartonellosis in Ancash, Peru. Trans.R.Soc.Trop Med Hyg, 98, 116-124. (Abstract)
16. Garcia,L., Kindt,A., Bermudez,H., Llanos-Cuentas,A., De Doncker,S., Arevalo,J., Wilber Quispe,T.K. and Dujardin,J.C. (2004) Culture-independent species typing of neotropical Leishmania for clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J Clin.Microbiol., 42, 2294-2297. (Abstract)
17. Soto,T.A., Solari,Z.L., Mendoza,R.D., Llanos-Cuentas,A. and Magill,A. (2004) Evaluation of the rapid diagnostic test OptiMAL for diagnosis of malaria due to Plasmodium vivax. Braz.J Infect.Dis., 8, 151-155. (Abstract)
18. de Wet,N., Llanos-Cuentas,A., Suleiman,J., Baraldi,E., Krantz,E.F., Della,N.M. and Diekmann-Berndt,H. (2004) A randomized, double-blind, parallel-group, dose-response study of micafungin compared with fluconazole for the treatment of esophageal candidiasis in HIV-positive patients. Clin.Infect.Dis., 39, 842-849. (Abstract)
19. Andersen,E.M., Cruz-Saldarriaga,M., Llanos-Cuentas,A., Luz-Cjuno,M., Echevarria,J., Miranda-Verastegui,C., Colina,O. and Berman,J.D. (2005) Comparison of meglumine antimoniate and pentamidine for peruvian cutaneous leishmaniasis. Am J Trop Med Hyg, 72, 133-137. (Abstract)
20. Decuypere,S., Vandesompele,J., Yardley,V., De Doncker,S., Laurent,T., Rijal,S., Llanos-Cuentas,A., Chappuis,F., Arevalo,J. and Dujardin,J.C. (2005) Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, in press.

HUG

1. Chappuis,F., Udayraj,N., Stietenroth,K., Meussen,A. and Bovier,P. (2005) Eflornithine is safer than melarsoprol for the treatment of second stage Trypanosoma brucei gambiense human African trypanosomiasis. Clin.Infect.Dis., in press.
2. Decuypere,S., Vandesompele,J., Yardley,V., De Doncker,S., Laurent,T., Rijal,S., Llanos-Cuentas,A., Chappuis,F., Arevalo,J. and Dujardin,J.C. (2005) Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, in press.
3. Dijkstra,J.A., Chappuis,F. and Loutan,L. (2005) Vaccine-reventable diseases in long-term expatriates. J Travel Med, 12, S47-57.
4. Chappuis,F., Loutan,L., Simarro,P., Lejon,V. and Buscher,P. (2005) Options for field diagnosis of human african trypanosomiasis. Clin.Microbiol.Rev., 18, 133-146. (Abstract)
5. Schmid,C., Richer,M., Bilenge,C.M., Josenando,T., Chappuis,F., Manthelot,C.R., Nangouma,A., Doua,F., Asumu,P.N., Simarro,P.P. et al. (2005) Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human african trypanosomiasis: confirmation from a multinational study (IMPAMEL II). J Infect.Dis., 191, 1922-1931. (Abstract)
6. Jackson,Y., Chappuis,F. and Loutan,L. (2004) African tick-bite fever: four cases among Swiss travelers returning from South Africa. J Travel Med, 11, 225-228. (Abstract)
7. Sharma,S.K., Chappuis,F., Jha,N., Bovier,P.A., Loutan,L. and Koirala,S. (2004) Impact of snake bites and determinants of fatal outcomes in southeastern Nepal. Am J Trop Med Hyg, 71, 234-238. (Abstract)
8. Rijal,S., Boelaert,M., Regmi,S., Karki,B.M., Jacquet,D., Singh,R., Chance,M.L., Chappuis,F., Hommel,M., Desjeux,P. et al. (2004) Evaluation of a urinary antigen-based latex agglutination test in the diagnosis of kala-azar in eastern Nepal. Trop Med Int.Health, 9, 724-729. (Abstract)
9. Chappuis,F., Justafre,J.C., Duchunstang,L., Loutan,L. and Taylor,W.R. (2004) Dengue fever and long thoracic nerve palsy in a traveler returning from Thailand. J Travel Med, 11, 112-114. (Abstract)
10. Boelaert,M., Rijal,S., Regmi,S., Singh,R., Karki,B., Jacquet,D., Chappuis,F., Campino,L., Desjeux,P., Le Ray,D. et al. (2004) A comparative study of the effectiveness of diagnostic tests for visceral leishmaniasis. Am J Trop Med Hyg, 70, 72-77. (Abstract)
11. Chappuis,F., Stivanello,E., Adams,K., Kidane,S., Pittet,A. and Bovier,P.A. (2004) Card agglutination test for trypanosomiasis (CATT) end-dilution titer and cerebrospinal fluid cell count as predictors of human African Trypanosomiasis (Trypanosoma brucei gambiense) among serologically suspected individuals in southern Sudan. Am J Trop Med Hyg, 71, 313-317. (Abstract)
12. Rijal,S., Chappuis,F., Singh,R., Boelaert,M., Loutan,L. and Koirala,S. (2003) Sodium stibogluconate cardiotoxicity and safety of generics. Trans.R.Soc.Trop Med Hyg, 97, 597-598. (Abstract)
13. Rijal,S., Chappuis,F., Singh,R., Bovier,P.A., Acharya,P., Karki,B.M., Das,M.L., Desjeux,P., Loutan,L. and Koirala,S. (2003) Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline. Trans.R.Soc.Trop Med Hyg, 97, 350-354. (Abstract)
14. Chappuis,F., Loutan,L., Samii,K. and Rougemont,A.L. (2003) The use of a rapid diagnostic test to determine malaria as a cause of death. J Travel Med, 10, 356-357. (Abstract)
15. Chappuis,F., Rijal,S., Singh,R., Acharya,P., Karki,B.M., Das,M.L., Bovier,P.A., Desjeux,P., Le Ray,D., Koirala,S. et al. (2003) Prospective evaluation and comparison of the direct agglutination test and an rK39-antigen-based dipstick test for the diagnosis of suspected kala-azar in Nepal. Trop Med Int.Health, 8, 277-285. (Abstract)
16. Schallig,H.D., Schoone,G.J., Kroon,C.C., Hailu,A., Chappuis,F. and Veeken,H. (2001) Development and application of 'simple' diagnostic tools for visceral leishmaniasis. Med Microbiol.Immunol.(Berl), 190, 69-71. (Abstract)
17. Chappuis,F., Pittet,A., Bovier,P.A., Adams,K., Godineau,V., Hwang,S.Y., Magnus,E. and Buscher,P. (2002) Field evaluation of the CATT/Trypanosoma brucei gambiense on blood-impregnated filter papers for diagnosis of human African trypanosomiasis in southern Sudan. Trop Med Int.Health, 7, 942-948. (Abstract)
18. Chappuis,F., Farinelli,T. and Loutan,L. (2001) Ivermectin treatment of a traveler who returned from Peru with cutaneous gnathostomiasis. Clin.Infect.Dis., 33, E17-E19. (Abstract)

References

A. Leishmaniasis

1. Ilgoutz,S.C. and McConville,M.J. (2001) Function and assembly of the Leishmania surface coat. Int.J Parasitol, 31, 899-908. (Abstract)
2. Kamhawi,S., Ramalho-Ortigao,M., Pham,V.M., Kumar,S., Lawyer,P.G., Turco,S.J., Barillas-Mury,C., Sacks,D.L. and Valenzuela,J.G. (2004) A role for insect galectins in parasite survival. Cell, 119, 329-341. (Abstract)
3. Sacks,D. and Kamhawi,S. (2001) Molecular aspects of parasite-vector and vector-host interactions in leishmaniasis. Annu.Rev.Microbiol., 55, 453-483. (Abstract)
4. Yao,C., Donelson,J.E. and Wilson,M.E. (2003) The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function. Mol.Biochem.Parasitol, 132, 1-16. (Abstract)
5. Mosser,D.M. and Brittingham,A. (1997) Leishmania, macrophages and complement: a tale of subversion and exploitation. Parasitology, 115 Suppl, S9-23. (Abstract)
6. Lewis,D.J. and Ward,R.D. (1987) Transmissions and vectors. In Killick-Kendrick,R. (ed.), The leishmaniases in biology and medicine. Academic Press, London, pp. 235-262.
7. Cameron,M.M., Pessoa,F.A., Vasconcelos,A.W. and Ward,R.D. (1995) Sugar meal sources for the phlebotomine sandfly Lutzomyia longipalpis in Ceara State, Brazil. Med Vet.Entomol., 9, 263-272. (Abstract)
8. Shaw,J.J. (1987) Codes for hosts of Leishmania. In Killick-Kendrick,R. (ed.), The leishmaniases in biology and medicine. Academic Press, London, pp. 465-472.
9. Lainson,R. and Shaw,J.J. (1987) Evolution, classification and geographical distribution. In Killick-Kendrick,R. (ed.), The leishmaniases in biology and medicine. Academic Press, London, pp. 2-120.
10. Tibayrenc,M. and Ayala,F.J. (1999) Evolutionary genetics of Trypanosoma and Leishmania. Microbes.Infect., 1, 465-472. (Abstract)
11. Pearson,R.D. and Sousa,A.Q. (1996) Clinical spectrum of Leishmaniasis. Clin.Infect.Dis., 22, 1-13. (Abstract)
12. Ridley,D.S. (1987) Pathology. In Killick-Kendrick,R. (ed.), The leishmaniases in biology and medicine. Academic Press, London, pp. 665-702.
13. Croft,S.L. and Coombs,G.H. (2003) Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol, 19, 502-508. (Abstract)
14. Singh,S. and Sivakumar,R. (2004) Challenges and new discoveries in the treatment of leishmaniasis. J Infect.Chemother., 10, 307-315. (Abstract)
15. Sundar,S. (2001) Drug resistance in Indian visceral leishmaniasis. Trop Med Int.Health, 6, 849-854. (Abstract)
16. Sundar,S., Mehta,H., Suresh,A.V., Singh,S.P., Rai,M. and Murray,H.W. (2004) Amphotericin B treatment for Indian visceral leishmaniasis: conventional versus lipid formulations. Clin.Infect.Dis., 38, 377-383. (Abstract)
17. Coler,R.N. and Reed,S.G. (2005) Second-generation vaccines against leishmaniasis. Trends Parasitol, 21, 244-249. (Abstract)
18. Modabber,F. (1995) Vaccines against leishmaniasis. Ann.Trop Med Parasitol, 89 Suppl 1, 83-88. (Abstract)
19. Valenzuela,J.G., Belkaid,Y., Garfield,M.K., Mendez,S., Kamhawi,S., Rowton,E.D., Sacks,D.L. and Ribeiro,J.M. (2001) Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein. J Exp.Med, 194, 331-342. (Abstract)
20. Vioukov,V.N. (1987) Control of transmission. In Killick-Kendrick,R. (ed.), The leishmaniases in biology and medicine. Academic Press, London, pp. 910-928.
21. Desjeux,P. (2001) The increase in risk factors for leishmaniasis worldwide. Trans.R.Soc.Trop Med Hyg, 95, 239-243. (Abstract)
22. Peterson,A.T. and Shaw,J. (2003) Lutzomyia vectors for cutaneous leishmaniasis in Southern Brazil: ecological niche models, predicted geographic distributions, and climate change effects. Int.J Parasitol, 33, 919-931. (Abstract)
23. Reithinger,R., Mohsen,M., Aadil,K., Sidiqi,M., Erasmus,P. and Coleman,P.G. (2003) Anthroponotic cutaneous leishmaniasis, Kabul, Afghanistan. Emerg.Infect.Dis., 9, 727-729. (Abstract)
24. Zijlstra,E.E. and El Hassan,A.M. (2001) Leishmaniasis in Sudan. Visceral leishmaniasis. Trans.R.Soc.Trop Med Hyg, 95 Suppl 1, S27-S58. (Abstract)
25. Haimeur,A. and Ouellette,M. (1998) Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate. Antimicrob.Agents Chemother., 42, 1689-1694. (Abstract)
26. Haimeur,A., Brochu,C., Genest,P., Papadopoulou,B. and Ouellette,M. (2000) Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol.Biochem.Parasitol, 108, 131-135. (Abstract)
27. Tibayrenc,M., Ben Abderrazak,S., Guerrini,F. and Banuls,A. (1993) Leishmania and the clonal theory of parasitic protozoa. Arch.Inst.Pasteur Tunis, 70, 375-382. (Abstract)
28. Dujardin,J.C., Banuls,A.L., Llanos-Cuentas,A., Alvarez,E., DeDoncker,S., Jacquet,D., Le Ray,D., Arevalo,J. and Tibayrenc,M. (1995) Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru. Acta Trop, 59, 293-307. (Abstract)
29. Desjeux,P. and Alvar,J. (2003) Leishmania/HIV co-infections: epidemiology in Europe. Ann.Trop Med Parasitol, 97 Suppl 1, 3-15. (Abstract)
30. Fernandez-Guerrero,M.L., Robles,P., Rivas,P., Mojer,F., Muniz,G. and de Gorgolas,M. (2004) Visceral leishmaniasis in immunocompromised patients with and without AIDS: a comparison of clinical features and prognosis. Acta Trop, 90, 11-16. (Abstract)
31. Alvar,J. and Jimenez,M. (1994) Could infected drug-users be potential Leishmania infantum reservoirs? AIDS, 8, 854. (Abstract)
32. Ritmeijer,K., Veeken,H., Melaku,Y., Leal,G., Amsalu,R., Seaman,J. and Davidson,R.N. (2001) Ethiopian visceral leishmaniasis: generic and proprietary sodium stibogluconate are equivalent; HIV co-infected patients have a poor outcome. Trans.R.Soc.Trop Med Hyg, 95, 668-672. (Abstract)

B. Drug resistance Leishmania

1. Olliaro,P.L. and Bryceson,A.D. (1993) Practical progress and new drugs for changing patterns of leishmaniasis. Parasitol Today, 9, 323-328. (Abstract)
2. Sundar,S. (2001) Drug resistance in Indian visceral leishmaniasis. Trop Med Int.Health, 6, 849-854. (Abstract)
3. Rijal,S., Chappuis,F., Singh,R., Bovier,P.A., Acharya,P., Karki,B.M., Das,M.L., Desjeux,P., Loutan,L. and Koirala,S. (2003) Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline. Trans.R.Soc.Trop Med Hyg, 97, 350-354. (Abstract)
4. Llanos-Cuentas, E. A. (1991) Tratamiento de Leishmaniasis mucosa: Análisis de los factores asociados con la respuesta terapéutica a los antimoniales pentavalentes. Thesis to obtain Doctoral degree in Medicine, Universidad Peruana Cayetano Heredia.
5. Lira,R., Sundar,S., Makharia,A., Kenney,R., Gam,A., Saraiva,E. and Sacks,D. (1999) Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J Infect.Dis., 180, 564-567. (Abstract)
6. Perez-Victoria,F.J., Castanys,S. and Gamarro,F. (2003) Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug. Antimicrob.Agents Chemother., 47, 2397-2403. (Abstract)
7. Veeken,H., Ritmeijer,K., Seaman,J. and Davidson,R. (2000) A randomized comparison of branded sodium stibogluconate and generic sodium stibogluconate for the treatment of visceral leishmaniasis under field conditions in Sudan. Trop Med Int.Health, 5, 312-317. (Abstract)
8. Jackson,J.E., Tally,J.D., Ellis,W.Y., Mebrahtu,Y.B., Lawyer,P.G., Were,J.B., Reed,S.G., Panisko,D.M. and Limmer,B.L. (1990) Quantitative in vitro drug potency and drug susceptibility evaluation of Leishmania ssp. from patients unresponsive to pentavalent antimony therapy. Am J Trop Med Hyg, 43, 464-480. (Abstract)
9. Grogl,M., Thomason,T.N. and Franke,E.D. (1992) Drug resistance in leishmaniasis: its implication in systemic chemotherapy of cutaneous and mucocutaneous disease. Am J Trop Med Hyg, 47, 117-126. (Abstract)
10. Faraut-Gambarelli,F., Piarroux,R., Deniau,M., Giusiano,B., Marty,P., Michel,G., Faugere,B. and Dumon,H. (1997) In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis. Antimicrob.Agents Chemother., 41, 827-830. (Abstract)
11. Croft,S.L., Yardley,V. and Kendrick,H. (2002) Drug sensitivity of Leishmania species: some unresolved problems. Trans.R.Soc.Trop Med Hyg, 96 Suppl 1, S127-S129. (Abstract)
12. Coons,T., Hanson,S., Bitonti,A.J., McCann,P.P. and Ullman,B. (1990) Alpha-difluoromethylornithine resistance in Leishmania donovani is associated with increased ornithine decarboxylase activity. Mol.Biochem.Parasitol, 39, 77-89. (Abstract)
13. Detke,S., Chaudhuri,G., Kink,J.A. and Chang,K.P. (1988) DNA amplification in tunicamycin-resistant Leishmania mexicana. Multicopies of a single 63-kilobase supercoiled molecule and their expression. J Biol.Chem., 263, 3418-3424. (Abstract)
14. Ellenberger,T.E. and Beverley,S.M. (1989) Multiple drug resistance and conservative amplification of the H region in Leishmania major. J Biol.Chem., 264, 15094-15103. (Abstract)
15. Grogl,M., Oduola,A.M., Cordero,L.D. and Kyle,D.E. (1989) Leishmania spp.: development of pentostam-resistant clones in vitro by discontinuous drug exposure. Exp.Parasitol, 69, 78-90. (Abstract)
16. Haimeur,A. and Ouellette,M. (1998) Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate. Antimicrob.Agents Chemother., 42, 1689-1694. (Abstract)
17. Ainanshe,O.A., Jennings,F.W. and Holmes,P.H. (1992) Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia. Trop Anim Health Prod., 24, 65-73. (Abstract)
18. Gramiccia,M., Gradoni,L. and Orsini,S. (1992) Decreased sensitivity to meglumine antimoniate (Glucantime) of Leishmania infantum isolated from dogs after several courses of drug treatment. Ann.Trop Med Parasitol, 86, 613-620. (Abstract)
19. Zhang,Z.Q., Giroud,C. and Baltz,T. (1993) Trypanosoma evansi: in vivo and in vitro determination of trypanocide resistance profiles. Exp.Parasitol, 77, 387-394. (Abstract)
20. Gladysheva,T.B., Oden,K.L. and Rosen,B.P. (1994) Properties of the arsenate reductase of plasmid R773. Biochemistry, 33, 7288-7293. (Abstract)
21. Rosen,B.P. (1995) Resistance mechanisms to arsenicals and antimonials. J Basic Clin.Physiol Pharmacol., 6, 251-263. (Abstract)
22. Xu,C., Zhou,T., Kuroda,M. and Rosen,B.P. (1998) Metalloid resistance mechanisms in prokaryotes. J Biochem.(Tokyo), 123, 16-23. (Abstract)
23. Gourbal,B., Sonuc,N., Bhattacharjee,H., Legare,D., Sundar,S., Ouellette,M., Rosen,B.P. and Mukhopadhyay,R. (2004) Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin. J Biol.Chem., 279, 31010-31017. (Abstract)
24. Rosen,B.P. (2002) Biochemistry of arsenic detoxification. FEBS Lett., 529, 86-92. (Abstract)
25. Marquis,N., Gourbal,B., Rosen,B.P., Mukhopadhyay,R. and Ouellette,M. (2005) Modulation in aquaglyceroporin AQP1 gene expression in drug resistant Leishmania. Mol.Microbiol., in press.
26. Grondin,K., Haimeur,A., Mukhopadhyay,R., Rosen,B.P. and Ouellette,M. (1997) Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO J, 16, 3057-3065. (Abstract)
27. Guimond,C., Trudel,N., Brochu,C., Marquis,N., El Fadili,A., Peytavi,R., Briand,G., Richard,D., Messier,N., Papadopoulou,B. et al. (2003) Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays. Nucleic Acids Res., 31, 5886-5896. (Abstract)
28. Haimeur,A., Guimond,C., Pilote,S., Mukhopadhyay,R., Rosen,B.P., Poulin,R. and Ouellette,M. (1999) Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania. Mol.Microbiol., 34, 726-735. (Abstract)
29. Haimeur,A., Brochu,C., Genest,P., Papadopoulou,B. and Ouellette,M. (2000) Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol.Biochem.Parasitol, 108, 131-135. (Abstract)
30. Legare,D., Papadopoulou,B., Roy,G., Mukhopadhyay,R., Haimeur,A., Dey,S., Grondin,K., Brochu,C., Rosen,B.P. and Ouellette,M. (1997) Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania. Exp.Parasitol, 87, 275-282. (Abstract)
31. Mukhopadhyay,R., Dey,S., Xu,N., Gage,D., Lightbody,J., Ouellette,M. and Rosen,B.P. (1996) Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proc.Natl.Acad.Sci.U.S.A, 93, 10383-10387. (Abstract)
32. El Fadili,K., Messier,N., Leprohon,P., Roy,G., Guimond,C., Trudel,N., Saravia,N.G., Papadopoulou,B., Legare,D. and Ouellette,M. (2005) Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes. Antimicrob.Agents Chemother., 49, 1988-1993. (Abstract)
33. Tibayrenc,M. (1996) Towards a unified evolutionary genetics of microorganisms. Annu.Rev.Microbiol., 50, 401-429. (Abstract)
34. Sereno,D. and Lemesre,J.L. (1997) In vitro life cycle of pentamidine-resistant amastigotes: stability of the chemoresistant phenotypes is dependent on the level of resistance induced. Antimicrob.Agents Chemother., 41, 1898-1903. (Abstract)
35. Moreira,E.S., Anacleto,C. and Petrillo-Peixoto,M.L. (1998) Effect of glucantime on field and patient isolates of New World Leishmania: use of growth parameters of promastigotes to assess antimony susceptibility. Parasitol Res., 84, 720-726. (Abstract)
36. Kink,J.A. and Chang,K.P. (1987) Tunicamycin-resistant Leishmania mexicana amazonensis: expression of virulence associated with an increased activity of N-acetylglucosaminyltransferase and amplification of its presumptive gene. Proc.Natl.Acad.Sci.U.S.A, 84, 1253-1257. (Abstract)
37. Wilson,C.M., Volkman,S.K., Thaithong,S., Martin,R.K., Kyle,D.E., Milhous,W.K. and Wirth,D.F. (1993) Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol.Biochem.Parasitol, 57, 151-160. (Abstract)